Malignant pleural
mesothelioma NCCN Guidelines:
The
National Comprehensive Cancer Network (NCCN) has guidelines for the diagnosis
and treatment of malignant pleural mesothelioma, a type of cancer caused by
exposure to asbestos. The guidelines aim to provide patients with the best
possible care, ensuring that all treatment plans are evidence-based and up-to-date.
Treatment recommendations are based on the stage of the cancer, as well as other factors such as a patient's overall health. For malignant pleural mesothelioma, these treatments may include surgery, chemotherapy, radiation therapy, and palliative care.
Surgery
is the preferred treatment option for early stages of mesothelioma cancer.
Surgical options can include removing the affected lung, or a portion of it, in
order to remove the tumor. In more advanced stages, surgery may not be an
option due to the extent of the tumor.
Chemotherapy
is also a common treatment option for malignant pleural mesothelioma, and can
be used alone or in combination with other therapies. The NCCN recommends using
drugs that are specifically approved for treating mesothelioma cancer, such as
Alimta and Cisplatin. Chemotherapy works by killing cancer cells and shrinking
tumors, allowing them to be more easily removed with surgery.
Radiation
therapy may also be used in certain cases of malignant pleural mesothelioma.
Radiation therapy works by destroying cancer cells in a targeted area. The NCCN
recommends external beam radiation, as well as internal radiation therapy when
appropriate.
Palliative
care is an important part of any treatment plan for malignant pleural mesothelioma.
This type of care is focused on relieving pain and other symptoms associated
with the cancer. Palliative care can include medications, physical therapy,
psychological counseling, and other forms of support.
The
NCCN guidelines are updated regularly and provide patients with the most
current information available on treatments for malignant pleural mesothelioma.
Patients should talk to their doctors about their individual treatment plans to
ensure they are receiving the best care possible. Depending on the stage of the disease and other factors,
different combinations of treatments may be necessary. It is important to note
that there is no known cure for malignant pleural mesothelioma, so treatment
focuses on alleviating symptoms and prolonging life. Nutrition can play a major
role in managing this type of cancer, as a balanced diet full of fruits and
vegetables can help keep energy levels high and reduce side effects from
treatments. Exercise can also help improve quality of life by reducing fatigue,
maintaining muscle strength, and reducing stress levels. There are various
types of clinical trials available for those who have been diagnosed with
mesothelioma cancer, so it’s important to speak to your doctor if you would
like to explore this option. Finally, it’s essential to seek out emotional
support during this difficult time - talking to loved ones and seeking out
counseling can be beneficial.
Malignant pleural
mesothelioma treatment:
Treating
malignant pleural mesothelioma can be complex and requires a combination of
treatments including surgery, radiation, chemotherapy, targeted therapy and
immunotherapy. The type of treatment plan a patient receives will depend on the
stage and type of mesothelioma they have, as well as their overall health.
The
National Comprehensive Cancer Network (NCCN) guidelines recommend a multimodal
approach for treating malignant pleural mesothelioma. Surgery is often used in
combination with other treatments such as radiation and/or chemotherapy to
maximize the benefit of treatment. Surgery may also be used to remove tumors
and improve symptoms.
Radiation
therapy may be used to shrink tumors before or after surgery. This is typically
done with a combination of external beam radiation and brachytherapy (internal
radiation). In some cases, radiation may be used instead of surgery.
Chemotherapy
is an important component of mesothelioma treatment and is often used in
combination with surgery and radiation. Chemotherapy drugs are used to kill
mesothelioma cells that remain after surgery. Common chemotherapy drugs used to
treat mesothelioma cancer include cisplatin, pemetrexed and gemcitabine.
Targeted
therapy is another option for treating malignant pleural mesothelioma. Targeted
therapy drugs are designed to target specific pathways in the cancer cells that
help them to grow, survive and spread. Examples of targeted therapies used in
mesothelioma treatment include bevacizumab and crizotinib.
Immunotherapy
is a newer form of treatment for mesothelioma cancer that has been showing
promise in clinical trials. Immunotherapy helps to boost the body’s natural
immune response so that it can more effectively fight off the cancer cells.
Examples of immunotherapies used in mesothelioma treatment include nivolumab
and ipilimumab.
The
best treatment plan for malignant pleural mesothelioma will depend on the
individual patient's diagnosis, stage of disease and overall health. It is
important to talk to your healthcare team about which treatment options are
right for you.
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