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Enhertu Breast Cancer Treatment: A Comprehensive
Guide
Introduction:
Breast cancer is a common form of cancer that
affects millions of women around the world. In recent years, there have been
significant advances in breast cancer treatment, and Enhertu is one of the
latest breakthroughs in breast cancer therapy. In this article, we will provide
you with a comprehensive guide to Enhertu breast cancer treatment.
What is Enhertu?
Enhertu (fam-trastuzumab deruxtecan-nxki) is a
medication used to treat HER2-positive breast cancer, a type of breast cancer
that is caused by a protein called HER2. Enhertu is a form of targeted therapy
that works by binding to the HER2 protein and delivering a chemotherapy drug
directly to the cancer cells, while sparing healthy cells from damage.
How does Enhertu work?
Enhertu works by delivering a potent chemotherapy
drug directly to the HER2-positive breast cancer cells. The drug, called
deruxtecan, is attached to a monoclonal antibody called trastuzumab, which
specifically targets HER2-positive cancer cells. When Enhertu binds to the HER2
protein, it delivers the deruxtecan drug directly to the cancer cells, where it
destroys them from the inside out.
Clinical trials:
Clinical trials have shown that Enhertu is highly
effective in treating HER2-positive breast cancer. In a phase 2 clinical trial,
Enhertu was tested on patients with advanced HER2-positive breast cancer who
had previously received other forms of treatment. The results showed that
Enhertu had a response rate of 60.9%, meaning that the cancer either shrank or
disappeared completely in over half of the patients.
Side effects:
As with any medication, Enhertu can cause side
effects. The most common side effects of Enhertu include nausea, fatigue, hair
loss, and a decrease in white blood cell count. In rare cases, Enhertu can
cause more serious side effects, such as lung damage or heart problems. It is
important to talk to your doctor about any potential side effects before
starting treatment with Enhertu.
Conclusion:
Enhertu is a promising new treatment for
HER2-positive breast cancer. It is highly effective, with clinical trials
showing that it can shrink or eliminate cancer in over half of patients. While
it can cause side effects, these are generally mild and can be managed with
proper medical care. If you or someone you know has HER2-positive breast
cancer, talk to your doctor about whether Enhertu may be a suitable treatment
option.
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