why is small cell carcinoma is so deadly:
Small cell lung
cancer, also known as small cell carcinoma, is a type of lung cancer that is
characterized by the small size of the cancer cells. It is an aggressive and
fast-growing cancer that typically starts in the bronchi, the larger airways of
the lungs.
One of the reasons
why small cell lung cancer is so deadly is because it is often found at an
advanced stage. The cancer cells can grow and spread quickly, and by the time
the cancer is diagnosed, it has often already spread to other parts of the body
such as the brain, bones, liver, or adrenal glands. This makes it difficult to
treat and results in a poor prognosis.
Another reason why
small cell lung cancer is so deadly is because it is often resistant to
treatment. The small cell lung cancer cells are able to evade the immune system
and traditional treatments such as surgery, radiation therapy, and chemotherapy
may not be effective.
Additionally, small
cell lung cancer is closely associated with smoking, and the majority of cases
occur in current or former smokers. The carcinogens present in tobacco smoke
damage the DNA in the cells of the lungs, leading to mutations that can cause
cancer.
Furthermore, small
cell lung cancer is a neuroendocrine tumor which is characterized by the
presence of small, round cells that have a high nuclear-to-cytoplasmic ratio
and hyperchromatic nuclei. It is also characterized by a high mitotic index and
the presence of neurosecretory granules in the cytoplasm. These features make
small cell lung cancer cells particularly resistant to chemotherapy and
radiation therapy.
In summary, small
cell lung cancer is so deadly because it is often found at an advanced stage,
it is often resistant to treatment, it is closely associated with smoking, and
it is a neuroendocrine tumor which makes it particularly resistant to chemotherapy
and radiation therapy. Additionally, the cancer cells can grow and spread
quickly, and by the time the cancer is diagnosed, it has often already spread
to other parts of the body.
small cell carcinoma survival rate:
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